Letrozole Tablets USP 2.5 mg

Letrozole Tablets USP 2.5 mg – Targeted Hormonal Therapy for Breast Cancer

Letrozole Tablets USP 2.5 mg is a prescription medication classified as a non-steroidal aromatase inhibitor, primarily used in the treatment of hormone receptor-positive breast cancer in postmenopausal women. By inhibiting the aromatase enzyme, letrozole effectively reduces estrogen production, thereby slowing or halting the growth of estrogen-dependent breast cancer cells.

✅ Key Benefits of Letrozole Tablets

• Adjuvant Treatment:
  Effective as an adjuvant therapy for early-stage hormone receptor-positive breast cancer in postmenopausal women.
  
• Extended Adjuvant Therapy:
  Beneficial for women who have completed 5 years of tamoxifen therapy, providing extended protection against cancer recurrence.
  
• Advanced Breast Cancer:
  Suitable for first and second-line treatment in postmenopausal women with advanced or metastatic breast cancer, especially after disease progression following anti-estrogen therapy.
  
• Convenient Dosage:
  Administered orally once daily, offering ease of use without the need for hospital visits.
  

🔹 Who Should Use Letrozole Tablets?

• Postmenopausal Women:
  Diagnosed with hormone receptor-positive early or advanced breast cancer.
  
• Patients Transitioning from Tamoxifen:
  Those who have completed 5 years of tamoxifen therapy and require extended adjuvant treatment.
  
• Individuals with Advanced Disease:
  Women experiencing disease progression after anti-estrogen therapy.
  

Note: Letrozole is not recommended for premenopausal women, pregnant or breastfeeding women, and individuals with known hypersensitivity to the drug.

🔹 How to Use Letrozole Tablets

• Dosage:
  The standard recommended dose is 2.5 mg once daily, taken at the same time each day.
  
• Administration:
  Can be taken with or without food. Swallow the tablet whole with water.
  
• Missed Dose:
  If a dose is missed, take it as soon as you remember. If it’s close to the time for the next dose, skip the missed dose. Do not double up to make up for a missed dose.
  

🔹 Potential Side Effects

Common Side Effects:

• Hot flashes
  
• Fatigue
  
• Dizziness
  
• Headache
  
• Joint or muscle pain
  
• Increased sweating
  
• Nausea
  
• Weight gain
  

Serious Side Effects:

• Bone thinning (osteoporosis)
  
• Elevated cholesterol levels
  
• Liver function abnormalities
  
• Cardiovascular events (e.g., heart attack, stroke)
  
• Severe allergic reactions
  

Important: Regular monitoring of bone density and cholesterol levels is recommended during treatment. Report any unusual symptoms to your healthcare provider promptly.

🔹 Warnings & Precautions

• Bone Health:
  Long-term use may lead to decreased bone mineral density. Bone health should be monitored, and preventive measures may be necessary.
  
• Liver Function:
  Use with caution in patients with liver impairment. Regular liver function tests are advised.
  
• Cardiovascular Risk:
  Patients with a history of cardiovascular disease should be closely monitored.
  
• Pregnancy & Lactation:
  Contraindicated in pregnant and breastfeeding women due to potential harm to the fetus or infant.
  

🔹 Why Choose Letrozole Tablets USP 2.5 mg?

Letrozole offers a targeted approach to treating hormone receptor-positive breast cancer in postmenopausal women. Its efficacy in both early and advanced stages of the disease, combined with a convenient oral dosing regimen, makes it a preferred choice for many patients and healthcare providers. By reducing estrogen levels, letrozole helps in slowing disease progression and reducing the risk of recurrence, thereby improving patient outcomes.