Premarin Vaginal Cream (Conjugated Estrogen)

Premarin Vaginal Cream 0.625 mg – Conjugated Estrogens for Menopausal Relief

Premarin Vaginal Cream contains 0.625 mg of conjugated estrogens per gram, specifically formulated to relieve vaginal symptoms of menopause such as dryness, burning, and irritation. As a localized hormone replacement therapy (HRT), it restores estrogen levels directly at the site of discomfort, helping improve vaginal health and sexual function.

Key Benefits:

• Targeted Relief: Effectively treats vaginal atrophy, dryness, itching, and painful intercourse (dyspareunia) related to menopause.
  
• Localized Estrogen Therapy: Minimizes systemic hormone exposure while delivering results where needed.
  
• User-Friendly: Includes a pre-measured applicator for easy and accurate intravaginal use.
  

Indications:

Premarin Vaginal Cream is recommended for:

• Treatment of atrophic vaginitis and kraurosis vulvae (vaginal tissue thinning and discomfort).
  
• Relief from moderate to severe dyspareunia due to menopausal vulvar and vaginal atrophy.
  
• Supplementing estrogen levels in women with estrogen deficiency when only local therapy is required.
  

Dosage and Administration:

• Standard Dosage: Typically, 0.5 g to 2 g is applied intravaginally once daily for 21 days, followed by a 7-day break.
  
• Method of Use: Insert the prescribed amount using the provided applicator. Dosage may be adjusted by a healthcare provider based on response and symptoms.
  

Always follow your doctor’s instructions and do not exceed the prescribed dosage.

Possible Side Effects:

While most users tolerate Premarin well, some may experience:

• Vaginal irritation, spotting, or discharge
  
• Headache or abdominal discomfort
  
• Breast tenderness or swelling
  

Rare but serious risks (especially with long-term use) may include:

• Blood clots
  
• Stroke or heart disease
  
• Increased risk of breast or endometrial cancer
  

Consult your physician immediately if you notice unusual vaginal bleeding or signs of a blood clot (chest pain, sudden headache, vision changes).

Warnings and Precautions:

• Not suitable for women with a history of breast cancer, blood clots, stroke, or liver disease.
  
• Smoking increases cardiovascular risk when using estrogen therapy.
  
• Use only under medical supervision, especially if you have a history of hormone-sensitive conditions.
  
• Discuss with your doctor before use during pregnancy or breastfeeding.
  

Storage Instructions:

• Store at 20°C to 25°C (68°F to 77°F) in a dry place.
  
• Keep out of reach of children.
  
• Do not use after the expiration date printed on the packaging.
  

Why Choose Premarin Vaginal Cream?

Premarin Vaginal Cream provides reliable, localized estrogen therapy with decades of clinical use supporting its effectiveness. It helps restore vaginal health, improve sexual comfort, and enhance quality of life for women experiencing menopausal changes—without the need for full-body hormone exposure.