Regorafenib 40 mg

Regorafenib 40 mg – Targeted Therapy for Advanced Cancers

Regorafenib 40 mg is a prescription-only oral medication developed by Bayer and marketed under the brand name Stivarga. It is a multi-kinase inhibitor that targets several enzymes involved in cancer cell growth and blood vessel formation. Regorafenib is used in the treatment of various advanced cancers, including:

• Metastatic Colorectal Cancer (CRC): For patients who have previously received standard therapies.
  
• Advanced Gastrointestinal Stromal Tumors (GISTs): For patients who have failed other treatments.
  
• Advanced Hepatocellular Carcinoma (HCC): For patients previously treated with sorafenib.
  

Key Features:

• Active Ingredient: Regorafenib 40 mg per tablet
  
• Formulation: Oral tablet
  
• Pack Size: Typically 28 tablets per bottle
  
• Manufacturer: Bayer
  
• Use: For the treatment of advanced cancers as specified above
  

Dosage and Administration:

The recommended dosage of Regorafenib 40 mg is:

• Metastatic Colorectal Cancer (CRC): 160 mg once daily for the first 3 weeks of each 4-week cycle, followed by 1 week off treatment.
  
• Advanced GISTs and HCC: Similar dosing regimen as CRC, adjusted based on individual patient tolerance and response.
  

Always follow your healthcare provider’s instructions regarding dosage and administration.

Side Effects:

Common side effects may include:

• Hand-Foot Syndrome: Redness, swelling, and pain on the palms of the hands or soles of the feet.
  
• Diarrhea
  
• Fatigue
  
• Loss of appetite
  
• Hypertension (high blood pressure)
  
• Mouth sores (mucositis)
  
• Weight loss
  
• Infection
  

Serious side effects can include:

• Liver toxicity: Elevated liver enzymes or jaundice.
  
• Severe bleeding
  
• Intestinal perforation
  
• Heart problems
  

Regular monitoring by your healthcare provider is essential during treatment.

Precautions:

Before using Regorafenib 40 mg, inform your doctor if you have:

• Liver problems: As regorafenib can affect liver function.
  
• Heart issues: Including a history of heart attacks or high blood pressure.
  
• Bleeding disorders
  
• History of gastrointestinal perforations
  

Use during pregnancy and breastfeeding is not recommended unless clearly needed. Discuss potential risks with your healthcare provider.

Storage:

Store Regorafenib 40 mg at room temperature, away from moisture and heat. Keep out of reach of children.

Price:

Regorafenib 40 mg is available at various online pharmacies. Prices may vary; it’s advisable to compare prices and consult with your healthcare provider before purchasing.

Conclusion:

Regorafenib 40 mg offers a targeted approach to treating advanced cancers, helping to inhibit tumor growth and improve patient outcomes. Always use under the supervision of a healthcare professional and adhere to prescribed dosages.